Botulinumtoxin Botox®

A biological bacterial protein inhibits nerve signals.

What is Botulinumtoxin("Botox")?

It is a bacterially produced bioprotein with a potent and specifically inhibitory effect on the transmission of nervous signals to muscle cells and glands. The high molecular weight protein resembles the etanustoxin . The American pharmaceutical company Allergan received the first approval of producing it as medicine. The medicine has the brand name Botox. Under this designation, it’s muscle relaxant function is known. In Germany, six medicines containing Botulinumtoxin A got approval.

Botulinumtoxin A: Application for facial wrinkles

Treatment time:	From 15 min
Clinic stay:	Outpatient
Anesthesia:	Partially
After treatment:	-
Sports:	From the 1st day
Costs:	From 220 €

Botulinumtoxin A / Botox is used through a dose- and targeted application to deliberately relieve certain mimic muscles. This allows a fresher appearance. The long-term, low-dose Botulinumtoxin treatment gives an adult face longer youthful smooth. In combination with a healthy lifestyle and with a Botulinumtoxin wrinkle treatment or Botulinumtoxin deflection, an external "slow aging" is possible.

How does botulinum toxin work?

A part of the Botulintoxin A protein binds to molecules in the signal-transmitting channel of the acetylcholinergic synapses. This binding of Botulinumtoxin irreversibly blocks the transmission of nerve signals. This means that signal transmission is no longer possible due to the Botulinumtoxin is filled into channel. The number of blocked channels correlates with the amount of medicine are used (Botulinumtoxin dosage). Acetylcholinergic synapses are found on neuromuscular end plates, also within the musculature and in the gland cells.

How can wrinkles be treated with Botulinumtoxin?

The wrinkle treatment with Botulinumtoxin makes use of the inhibitory effect of Botulinumtoxin on nerve signals. By precisely injecting the neurotoxins into the mimic muscles, specifically folding-forming muscles, depending on the dose, are to be weakened or completely stopped. Consequently allows buckling and upsetting movements through the mimic muscles and smoothen skin wrinkles.

Botulinumtoxin is suitable for which facial wrinkles?

The domain of wrinkle treatment with Botulinumtoxin / Botox is the upper face. Especially the treatment for Frown Lines, Forehead Lines and Crows Feet has good result. Other fields of application of Botulinumtoxin in aesthetic medicine are underlip wrinkles, smoking wrinkles and chin wrinkles. In addition to wrinkle treatment, it is possible to raise the eyebrows or to narrow the face by treating the excess masticatory muscles. The treatment around the mouth and in the lower face and on the chin line should get consultation with experts. Asymmetries are the basic rule, rather than the exception. Platysms on the neck (Turkey's neck) can be loosened with Botulinumtoxin, to allow neck skin reappears. In addition, excessive sweating can usually be successfully treated with Botulinumtoxin.

Is wrinkle treatment with Botulinumtoxin painful?

The pain threshold is individually different. There are several injections with a very fine needle in the face skin to bear. Some patients feel the wrinkle treatment as painful, some hardly. An anesthetizing ointment has a good effect only in the eye and lip area. The prior cooling of the injection area for pain relief is not recommended to achieve a better effect of Botulinumtoxin wrinkle treatment.

How long can the effect of Botulinumtoxin last?

The effect of Botulinumtoxin on the synapses is irreversible and permanent. The recovery of the innervation of muscles or sweat glands depends on the new sprouting of the nerve endings. Depending on the dose injected, only a part of the nerve endings are paralyzed by Botulinumtoxin. The duration of the Botulinumtoxin effect depends on the dose injected and adaptability of the patient. The choice of the Botox is less critical. For follow-up treatment often just requires paralyzed partially innervated muscle groups, it will then generally stretch during the treatment interval. The complete nerve signal transmission depends on the dose, is usually restored within two to six months. The desire for a prolonged Botulinumtoxin effect is counteracted by the need to avoid a masked face or even a distracting Botulinumtoxin treatment. Our doctor will work together with the patient to develop a strategic treatment plan for wrinkle treatment or prevention.

When does the botulinum toxin effect begin?

In general, the muscle-weakening effect of Botulinumtoxin is seen on average after 5 to 7 days after the treatment. The desired smoothing of the wrinkles needs a few more days. The Botulinumtoxin effect is complete after about 14 days. From the day of the strongest limitation of the strength, the strength of the mimic muscles begins to increase again.

What side effects does Botulinumtoxin have?

The protein acts very specifically at certain synapses after endocytosis and cleavage. Here you can read very detailed information about the side effects of a botulinum toxin treatment http://www.faceshop.de/botox-hyaluron-info/botulinumtoxin-nebenwirkungen/

Who can conduct Botulinumtoxin injection?

Botulinumtoxin injection should only be given by professional doctor in certified clinics as this is a prescription medicine. Botulinumtoxin treatments with uncertified individuals or clinics are illegal. Botulinumtoxin from black market can be dangerous.

How do I find a specialist doctor?

Wrinkle treatments are performed by dermatologists, plastic surgeons and other specialists. With a clinic has the focus on non-surgical wrinkle treatment, you can expect great experience. Faceshop is a specialized clinic with the focus on wrinkle treatment, you can find us in Duesseldorf, Berlin, Frankfurt, Cologne and Dortmund.

How expensive is a botulinum toxin injection? What is the cost of Botulinumtoxin treatment?

The Botulinumtoxin treatment is relatively expensive. It costs roughly between 200 and 600 euros. In the year, an average spends is between 600 and 1200 euros. The price depends on the Botulinumtoxin units are used. In an experienced and specialized wrinkle treatment clinic, you can get a good treatment result with reasonable price. The sooner wrinkle treatment with Botulinumtoxin begins, the more likely it is that treatment costs are less expensive.

The Botulinumtoxin treatment should be done in the entire face and not just in one region. In places without substantial wrinkles, a pre-treatment is treated and the material used is very economical. More detailed information about costs and prices can be found on http://www.faceshop.de/kosten-und-preise/botox-behandlung/

How many units of Botulinumtoxin / Botox do I need?

Depending on whether you want to treat only individual areas or the entire face and the neck, usually between 5 and 100 Allergan units are consumed per treatment. Typical Botulinumtoxin A amounts are being used: eyebrows 15 units, neck 30 units, crows feet 20 units, forehead 20 units, smoking wrinkles 5 units, frown Lines 25 units and Armpit sweating 100 units.

For an optimally positive result, the partial dosage at the individually selected injection points is more important than the total dosage.

Which injection technique is right?

While in the early stages of wrinkle treatment with Botulinumtoxin, inject deeply under the muscle, this kind of subcutaneous technique of injection is common now. For have precise injection technique with good results, the physician should have a hands-on experience of approx. 1000 treatments including follow-up checks.